研究方向

特色研究方向:纳米医学

该方向主要研究功能型纳米颗粒在临床医学中的应用,主要包括:(1)磁性纳米颗粒辅助的现代器官深低温玻璃化保存技术;(2)磁性纳米颗粒辅助的空间快速复温技术;(3)纳米冷热疗;(4)纳米玻璃化保存技术;(5)纳米颗粒调控的冻融和传递现象。

图1 磁性纳米颗粒辅助的现代器官深低温玻璃化保存技术
图2 磁性纳米颗粒辅助的空间快速复温技术
图3 纳米冷热疗
图4 纳米颗粒调控的冻融和传递现象

相关论文

  1. Huang, H., Choi, J.K., Rao W., Zhao S.T., Agarwal P., Gang Zhao, and He, X*. Alginate hydrogel microencapsulation minimizes intracellular ice formation in embryonic stem cells during cryopreservation. Advanced Functional Materials, 2015, (SCI, IF: 11.805, accepted, 一区)
  2. Rao, W. Wang, H., Han, J., Zhao, S., Dumbleton, J., Agarwal, P., Zhang, W., Zhao, G., Yu, J., Zynger, D.L., Lu, X., and He, X.* Augmented cancer destruction by nanodrug surface-decorated with chitosan to target CD44+ cancer cells. ACS Nano, 2015, 9(6): 5725-5740 (SCI, IF: 12.881, 一区).
  3. Rao, W., Huang, H., Wang H., Zhao S.T, Dumbleton J., Zhao, G, and He, X*. Nanoparticle-mediated intracellular delivery enables cryopreservation of human adipose-derived stem cells using trehalose as the sole cryoprotectant. ACS Applied Materials & Interfaces, 2015, 7: 5017-5028 (SCI, IF: 6.723, 一区).
  4. Jianye Wang, Gang Zhao*, Ping Zhou, Yunxia Cao*, Dayong Gao. Effect of iron oxide nanoparticles on the membrane permeabilities of SF21 cells. Cryobiology. 2015 (SCI, IF: 1.587, minor revision)
  5. Tao Wang, Gang Zhao*, Zhongshan Deng, Cai Gao, Yunxia Cao, Dayong Gao*. Theoretical investigation of a novel mocrowave antenna aided cryovial for rapid and uniform rewarming of frozen cryoprotective agent solutions. Applied Thermal Engineering, 2015, 89: 968-977 (SCI, IF: 2.739, 二区).
  6. Tao Wang, Gang Zhao*. Numerical simulation on microwave rewarming of cryopreserved rabbit kidney with embedded superparamagnetic nanoparticles. Cryoletters, 2015, 36(3): 213-220 (SCI, IF: 1.140).
  7. Jingru Yi, Gang Zhao*. Effect of Hydroxyapatite Nanoparticles on Biotransport Phenomena in Freezing HeLa Cells. Journal of Nanotechnology in Engineering and Medicine, 2014, 5: 041003(1-7)
  8. Jingru Yi, Heyu Tang, Gang Zhao*. Influence of hydroxyapatite nanoparticles on the viscosity of dimethyl sulfoxide-H2O-NaCl and glycerol-H2O-NaCl ternary systems at subzero temperatures. Cryobiology, 2014, 69(2): 291-298.
  9. Cui Yue, Gang Zhao*, Jingru Yi, Cai Gao, Lingxiao Shen, Zhen Wang, Wei Liu. Effect of hydroxyapatite nanoparticles on osmotic responses of pig iliac endothelial cells. Cryobiology, 2014, 69(2): 273-280.
  10. Wao Wang, Gang Zhao*, Xin M. Liang, Yunpeng Xu, Yang Li, Heyu Tang, Rui Jiang, Dayong Gao*. Numerical simulation of the effect of superparamagnetic nanoparticles on microwave rewarming of cryopreserved tissues. Cryobiology, 2014 68(2): 234–243